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Mind Map
by
Zulhilmi Zainal
, created
more than 1 year ago
Mind Map on PHARMACOLOGICAL ASPECTS OF HYPOTHALAMUS / PITUITARY & ADRENAL DISORDERS, created by Zulhilmi Zainal on 04/14/2014.
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Zulhilmi Zainal
almost 11 years ago
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mind_map
2017-01-14T00:31:25Z
PHARMACOLOGICAL ASPECTS OF
HYPOTHALAMUS / PITUITARY & ADRENAL
DISORDERS
physiology
Growth Hormone
somatropin,somatrem(synthetic analog)
To improve growth in children
with GH deficiency
Adverse
Carpal tunnel syndrome, hyperglycemia
Somatostatin
Somatotropin releasing inhibiting hormone
Synthetic
1 Octreotide 2 Pegvisomant
Acromegaly. Carcinoid tumors.
Pancreatic tumors
uses
Adverse
sludge(gallstone)
ERGOT DERIVATIVES
(DOPAMINE AGONIST (D2)
Decrease prolactin
Bromocriptine
USES
Hyperprolactinemia
Parkinsonism
effecs
syncope,postural hypotension, psychosis
Vassopressin
ADH
Uses
Neurogenic DI(pituitary)(central DI)
Nephrogenic DI(impaired renal response to AVP)
Constrict blood vessel
Adverse
coronary vasospasm
uterine contraction
Desmopressin
selective (V2) agonist
Uses
DI(Central,pituitary)(DOC)
Bedwetting(children)
Adenocorticosteroids
MAGIC drug
ALL Disease usable
Synthesis
uses
Immunosuppression
TOXICITY
Acute withdrawal
cerebral edema
fever, myalgia
Prolonged usage
fluid/lyte disturbances, hypertension, hyperglycemia, glycosuria
peptic ulcers, osteoporosis (direct inhibition of osteoblasts)
myopathy, cataracts
Neurologic diseases
Pulmonary diseases
Renal disease
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